A New Formulation Based on Ozonated Sunflower Seed Oil: In Vitro Antibacterial and Safety Evaluation

Publication Cover

Ozone: Science & Engineering

The Journal of the International Ozone Association

Volume 39, 2017 - Issue 3

Authors: Francesca Serio, Graziano Pizzolante, Giuseppe Cozzolino, Maria D’Alba, Francesco Bagordo, Mattia De Giorgi, show all

Pages 139-147 | Received 16 Jun 2016, Accepted 12 Dec 2016, Accepted author version posted online: 16 Dec 2016, Published online: 27 Jan 2017


The objective of this study was to investigate the potential in vitro biological properties of Oz.Or.Oil 30, a new formulation composed of 30% ozonated sunflower seed oil, which is believed to keep skin smooth and moisturized, supporting repair processes, tissue regeneration and re-epithelialization of wounds. The antibacterial activity, the qualitative and quantitative evaluation of the cytotoxic effect of the formulation on cultures of Vero cells and 3T3 fibroblasts showed that Oz.Or.Oil 30 merits further in vivo study using clinical-laboratory correlations, because it could be suggested as an alternative therapy against bacterial and fungal diseases.


Purchase paper here:


To gain full access to this paper and other papers published by the IOA become a member of the IOA.  Membership info HERE.


Additional information on Ozonated Olive Oil can be found HERE